| Robustness and topology of the yeast cell cycle Boolean network. | |
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MedLine Citation:
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PMID: 19302794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Yeast cell cycle Boolean network was used as a case study of robustness to protein noise. Robustness was interpreted as involving stability of G1 steady state and sequence of gene expression from cell cycle START to stationary G1. A robustness measure to evaluate robustness strength of a network was proposed. Robust putative networks corresponding to the same steady state and sequence of gene expression of wild-type network were sampled. Architecture of wild-type yeast cell cycle network can be revealed by average topology profile of sampled robust putative networks. |
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Authors:
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Wen-Bin Lee; Jiun-Yan Huang |
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Publication Detail:
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Type: Journal Article Date: 2009-02-10 |
Journal Detail:
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Title: FEBS letters Volume: 583 ISSN: 1873-3468 ISO Abbreviation: FEBS Lett. Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-03-23 Completed Date: 2009-04-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: Netherlands |
Other Details:
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Languages: eng Pagination: 927-32 Citation Subset: IM |
Affiliation:
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Department of Computer Science and Information Engineering, Chung Hua University, Hsin Chu 300, Taiwan, ROC. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cell Cycle* Computer Simulation Saccharomyces cerevisiae / cytology*, genetics, metabolism* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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