| Robust control in bacterial regulatory circuits. | |
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MedLine Citation:
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PMID: 15063859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Robust control refers to regulatory systems that are insensitive to perturbations to the intra- or extra-cellular environment. It is generally believed that most cell regulatory circuits should possess some degree of robustness. Examples of robust control and the underlying mechanisms for achieving this robustness are only beginning to be uncovered. Various forms of robustness are associated with circuits based on negative and/or positive feedback, bi-functional enzymes, protein oligomerization and discrete or continuous control. |
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Authors:
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Mark Goulian |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in microbiology Volume: 7 ISSN: 1369-5274 ISO Abbreviation: Curr. Opin. Microbiol. Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-05 Completed Date: 2004-06-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9815056 Medline TA: Curr Opin Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 198-202 Citation Subset: IM |
Affiliation:
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Department of Physics and Institute for Medicine and Engineering, University of Pennsylvania, 209 S. 33rd Street, Philadelphia, PA 19104, USA. goulian@physics.upenn.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacteria
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genetics* Gene Expression Regulation, Bacterial / physiology* Transcription, Genetic / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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