| Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature. | |
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MedLine Citation:
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PMID: 21269596 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ritonavir therapy is not generally considered nephrotoxic. We report a case of acute kidney injury secondary to ritonavir, with kidney biopsy demonstrating extensive acute tubular injury. This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented. |
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Authors:
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T Shafi; M J Choi; L C Racusen; L A Spacek; C Berry; M Atta; D M Fine |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinical nephrology Volume: 75 Suppl 1 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-28 Completed Date: 2011-04-06 Revised Date: 2011-05-25 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 60-4 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21224-2780, USA. tshafi@jhmi.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Kidney Injury
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chemically induced*,
pathology Antiretroviral Therapy, Highly Active Biological Markers / blood Biopsy Creatinine / blood Drug Substitution HIV Infections / drug therapy* HIV Protease Inhibitors / adverse effects* Humans Kidney / drug effects*, pathology Kidney Tubules / drug effects, pathology Male Middle Aged Ritonavir / adverse effects* Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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5T32-DK-007732-12/DK/NIDDK NIH HHS; K23 DK083514-02/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/HIV Protease Inhibitors; 0/Ritonavir; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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