Document Detail

Ritodrine-induced leukopenia: a case report and literature review.
MedLine Citation:
PMID:  9041773     Owner:  NLM     Status:  MEDLINE    
Ritodrine hydrochloride, a beta 2-adrenergic receptor agonist, has been widely applied in the treatment of premature labor for many years and generally considered as a safe medication. It can however induce some serious side effects, such as pulmonary edema, myocardial ischemia, ketoacidosis, miscellaneous metabolic alterations, and leukopenia. This report presents a rare case of leukopenia in a Chinese woman as a result of low dose continuous intravenous infusion of ritodrine, in which the white blood cell count dropped rapidly and recovered quickly following the cessation of administration. The rapid and spontaneous reversal of leukopenia was most probably due to early recognition and intervention of this drug-induced side effect.
C D Wu; A S Chao; P J Cheng; Y K Soong
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital     Volume:  19     ISSN:  -     ISO Abbreviation:  Changgeng Yi Xue Za Zhi     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-09     Completed Date:  1997-05-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9809559     Medline TA:  Changgeng Yi Xue Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  388-91     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
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MeSH Terms
Adrenergic beta-Agonists / adverse effects*
Leukopenia / chemically induced*
Ritodrine / adverse effects*
Tocolytic Agents / adverse effects*
Reg. No./Substance:
0/Adrenergic beta-Agonists; 0/Tocolytic Agents; 26652-09-5/Ritodrine

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