Document Detail


Risks to the fetus of radiologic procedures used in the diagnosis of maternal venous thromboembolic disease.
MedLine Citation:
PMID:  2749594     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The diagnosis of suspected venous thromboembolic disease during pregnancy is problematic because of the fear of fetal irradiation with routine diagnostic procedures. In order to develop rational guidelines, we have calculated levels of radiation exposure to the fetus for the common diagnostic procedures and conducted a literature review to examine the fetal risks associated with these levels of radiation. A small increase in the relative risk of childhood cancer is suggested by a literature review of outcomes following low dose (less than 5 rads), in utero radiation exposure. With careful use of the available procedures, a diagnosis of venous thrombosis is possible with fetal radiation exposure of less than 0.50 rads and a diagnosis of pulmonary embolism is possible with fetal radiation exposure of less than 0.05 rads. The risk of such exposure is small, both in relative and absolute terms.
Authors:
J S Ginsberg; J Hirsh; A J Rainbow; G Coates
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thrombosis and haemostasis     Volume:  61     ISSN:  0340-6245     ISO Abbreviation:  Thromb. Haemost.     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-08-25     Completed Date:  1989-08-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7608063     Medline TA:  Thromb Haemost     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  189-96     Citation Subset:  IM    
Affiliation:
Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Female
Fetus / radiation effects*
Humans
Pregnancy
Pregnancy Complications, Hematologic / radiography*,  radionuclide imaging
Pulmonary Embolism / radiography,  radionuclide imaging
Radiation Injuries*
Risk Factors
Teratogens
Thromboembolism / radiography*,  radionuclide imaging
Chemical
Reg. No./Substance:
0/Teratogens
Comments/Corrections
Comment In:
Thromb Haemost. 1990 Feb 19;63(1):142   [PMID:  2187270 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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