| Risk stratification of severe acute rhinosinusitis unresponsive to oral antibiotics. | |
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MedLine Citation:
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PMID: 20233013 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONCLUSIONS: C-reactive protein (CRP) levels may predict the extent of acute rhinosinusitis disease in the computed tomography (CT) scans, as well as the specific symptom severity. High levels may direct the physician to change the treatment. OBJECTIVE: To establish tools to define 'high risk' patients suffering from acute rhinosinusitis. METHODS: Patients suffering from severe unresponsive acute rhinosinusitis filled in health-related quality of life questionnaires and rated their symptoms. Blood tests and CT scans were performed. We examined the value of imaging and inflammatory markers, especially CRP, as predictors of disease severity, defined by subjective and objective means; need for surgery; and occurrence of ocular complications. RESULTS: Thirty-two patients were prospectively recruited. A significant association was found between CRP levels, imaging scores, and symptoms severity. Neither ocular complications nor the need for surgery were present in the group with low CRP level. |
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Authors:
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Nir Hirshoren; Aviv Hirschenbein; Ron Eliashar |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 130 ISSN: 1651-2251 ISO Abbreviation: Acta Otolaryngol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-25 Completed Date: 2010-12-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: England |
Other Details:
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Languages: eng Pagination: 1065-9 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology/Head & Neck Surgery, Hadassah Ein-Kerem University Hospital, Jerusalem, 91120 Israel. drnir@hadassah.org.il |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents / therapeutic use Biological Markers / blood C-Reactive Protein / metabolism* Humans Middle Aged Prospective Studies Rhinitis / blood*, drug therapy, radiography* Risk Factors Sinusitis / blood*, drug therapy, radiography* Tomography, X-Ray Computed Treatment Failure Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Biological Markers; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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