Document Detail

Risk stratification and prevention of sudden death in hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  12047795     Owner:  NLM     Status:  MEDLINE    
Sudden unexpected death, often occurring in young, asymptomatic patients, is the most devastating facet of the natural history of hypertrophic cardiomyopathy, and appears to be the consequence of primary ventricular tachyarrhythmias arising in an electrically unstable myocardial substrate characterized by disorganized cellular architecture, ischemia, cell death, and replacement scarring. Although precise identification of all hypertrophic cardiomyopathy patients at high risk for a catastrophic event is a clinical challenge, effective treatment strategies for the prevention of sudden death with the implantable cardioverter-defibrillator are now available.
Barry J Maron
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology in review     Volume:  10     ISSN:  1061-5377     ISO Abbreviation:  Cardiol Rev     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-06-05     Completed Date:  2002-09-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-81     Citation Subset:  IM    
Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA.
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MeSH Terms
Cardiomyopathy, Hypertrophic / complications*,  prevention & control
Death, Sudden, Cardiac / etiology,  prevention & control*
Defibrillators, Implantable*
Electric Countershock / instrumentation
Risk Assessment
Tachycardia, Ventricular / complications*,  drug therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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