Document Detail


Risk of respiratory failure after repair of thoracoabdominal aortic aneurysms.
MedLine Citation:
PMID:  8053516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Multiple complications occur after repair of a thoracoabdominal aortic aneurysm, the most common of which is respiratory failure. METHODS: One hundred consecutive thoracoabdominal aneurysm repairs were studied retrospectively using univariate, bivariate, and multiple logarithmic regression analyses to identify factors associated with respiratory failure. RESULTS: The mean of days of intubation was 5.8 +/- 0.8 (mean +/- SEM), with a median of 2 days. Patients who developed respiratory failure (21%) had a 42% mortality compared with a 6% mortality in patients who did not develop respiratory failure (P < 0.001). Statistical analysis demonstrated a significant (P < 0.01) age difference between those with respiratory failure (71.9 +/- 1.6 years) and those without (65.5 +/- 1.3 years). Type II aneurysms occurred in 32% of patients, a 3.2-fold increase in relative risk compared with all other types of aneurysm. Seventy-nine percent of patients had a significant smoking history. Low forced vital capacity and forced expiratory volume were both significant variables in predicting respiratory failure, but neither chronic obstructive pulmonary disease nor emphysema was a predictive variable. Intraoperative blood transfusion (mean 10.5 +/- 0.8 units) was associated with respiratory failure (P = 0.05). Postoperative complications associated with respiratory failure were creatinine elevation and pneumonia. CONCLUSION: We conclude that the independent variables affecting respiratory failure after thoracoabdominal aneurysm repair are age, type of aneurysm, excessive intraoperative blood transfusions, creatinine elevation, and postoperative pneumonia.
Authors:
S R Money; K Rice; D Crockett; M Becker; A Abdoh; W Wisselink; F Kazmier; L Hollier
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  168     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-09-08     Completed Date:  1994-09-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  152-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Ochsner Medical Institutions, New Orleans, Louisiana.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Aortic Aneurysm, Abdominal / complications,  surgery*
Aortic Aneurysm, Thoracic / complications,  surgery*
Blood Transfusion
Forced Expiratory Volume
Humans
Intraoperative Care
Intubation, Intratracheal
Postoperative Complications / diagnosis,  etiology*,  mortality,  physiopathology
Preoperative Care
Regression Analysis
Respiratory Insufficiency / diagnosis,  etiology*,  mortality,  physiopathology
Retrospective Studies
Risk Factors
Survival Rate
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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