| Risk of postnatal exposure to Sarcocystis neurona and Neospora hughesi in horses. | |
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MedLine Citation:
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PMID: 15334837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate risk of exposure and age at first exposure to Sarcocystis neurona and Neospora hughesi and time to maternal antibody decay in foals. ANIMALS: 484 Thoroughbred and Warmblood foals from 4 farms in California. PROCEDURE: Serum was collected before and after colostrum ingestion and at 3-month intervals thereafter. Samples were tested by use of the indirect fluorescent antibody test; cutoff titers were > or = 40 and > or = 160 for S neurona and N hughesi, respectively. RESULTS: Risk of exposure to S neurona and N hughesi during the study were 8.2% and 3.1%, respectively. Annual rate of exposure was 3.1% for S neurona and 1.7% for N hughesi. There was a significant difference in the risk of exposure to S neurona among farms but not in the risk of exposure to N hughesi. Median age at first exposure was 1.2 years for S neurona and 0.8 years for N hughesi. Highest prevalence of antibodies against S neurona and N hughesi was 6% and 2.1 %, respectively, at a mean age of 1.7 and 1.4 years, respectively. Median time to maternal antibody decay was 96 days for S neurona and 91 days for N hughesi. There were no clinical cases of equine protozoal myeloenchaphlitis (EPM). CONCLUSIONS AND CLINICAL RELEVANCE: Exposure to S neurona and N hughesi was low in foals between birth and 2.5 years of age. Maternally acquired antibodies may cause false-positive results for 3 or 4 months after birth, and EPM was a rare clinical disease in horses < or = 2.5 years of age. |
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Authors:
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Paulo C Duarte; Patricia A Conrad; W David Wilson; Gregory L Ferraro; Andrea E Packham; Jeanne Bowers-Lepore; Tim E Carpenter; Ian A Gardner |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of veterinary research Volume: 65 ISSN: 0002-9645 ISO Abbreviation: Am. J. Vet. Res. Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-08-31 Completed Date: 2004-11-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375011 Medline TA: Am J Vet Res Country: United States |
Other Details:
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Languages: eng Pagination: 1047-52 Citation Subset: IM |
Affiliation:
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Departments of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Antibodies, Protozoan / blood*, immunology California Coccidiosis / immunology, veterinary* Fluorescent Antibody Technique, Indirect Horse Diseases / immunology, parasitology* Horses Immunity, Maternally-Acquired / immunology Neospora* Risk Assessment Sarcocystis* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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