| Risk of partial and complete hydatidiform molar pregnancy in relation to maternal age. | |
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MedLine Citation:
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PMID: 11843379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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All cases of first histologically confirmed complete and partial moles registered between 1985 and 1999 were identified from the database of a Trophoblastic Disease Registration Centre. The maternal age distribution at diagnosis was calculated for the 7916 molar pregnancies and compared with the maternal age distribution of an unselected population of women from a routine obstetric database. Likelihood ratios were calculated for complete and partial molar pregnancies by maternal age. A positive relationship was found between the risk of molar pregnancy and both upper and lower extremes of maternal age (> or = 45 years and < or = 15 years, respectively). This association, although present for both complete and partial moles, is much greater for complete mole at all maternal ages, and the degree of risk is much greater with older (> or = 45 years) rather than younger (< or = 15 years) maternal age. This study provides, for the first time, data regarding specific risk of partial versus complete hydatidiform mole with maternal age. |
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Authors:
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N J Sebire; M Foskett; R A Fisher; H Rees; M Seckl; E Newlands |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 109 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2002 Jan |
Date Detail:
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Created Date: 2002-02-14 Completed Date: 2002-03-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 99-102 Citation Subset: AIM; IM |
Affiliation:
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Department of Cancer Medicine, Imperial College School of Medicine at Charing Cross Hospital, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Distribution Chi-Square Distribution Child Female Humans Hydatidiform Mole / etiology* Maternal Age* Middle Aged Pregnancy Risk Factors |
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