Document Detail


Risk of parathyromatosis after fine-needle aspiration.
MedLine Citation:
PMID:  11270891     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reoperative surgery for hyperparathyroidism (HPT) is fraught with hazard. When preoperative imaging studies are inconclusive or patient comorbidities are extensive fine needle-aspiration (FNA) is helpful to confirm the presence of suspected parathyroid tissue in the neck. Some surgeons refrain from using FNA because of the concern of tissue implantation (parathyromatosis). A retrospective review (1984-1996) of all patients diagnosed with HPT undergoing FNA of suspected parathyroid tissue was performed to document whether a correlation exists between FNA of suspected parathyroid tissue and subsequent development of parathyromatosis. Parathyromatosis was considered to have occurred when proven by histology or suspected on the basis of clinical studies. Of 81 patients with HPT undergoing ultrasound-guided FNA to assess abnormalities in the neck 41 patients with confirmed parathyroid tissue were identified. The indications for FNA in these 41 patients were: prior failed cervical exploration (n = 33), prior neck surgery and/or radiation (n = 2), inconclusive noninvasive imaging studies (n = 15), and severe comorbidities (n = 8). Mean follow-up was 5.8 years. No case of FNA-induced parathyromatosis was identified. FNA is useful to confirm the presence of parathyroid tissue in very select patients with hyperparathyroidism. FNA often eliminates the need for other imaging studies, may prevent a needless or likely fruitless re-exploration, and does not cause parathyromatosis.
Authors:
M L Kendrick; J W Charboneau; K J Curlee; J A van Heerden; D R Farley
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  67     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-28     Completed Date:  2001-04-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  290-3; discussion 293-4     Citation Subset:  IM    
Affiliation:
Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Biopsy, Needle / adverse effects*,  methods,  standards
Calcium / blood
Choristoma / etiology*
Female
Humans
Hyperparathyroidism / blood,  pathology*,  surgery,  ultrasonography*
Male
Middle Aged
Neck*
Patient Selection
Reoperation / adverse effects
Retrospective Studies
Risk Factors
Treatment Outcome
Ultrasonography, Interventional / adverse effects*,  methods,  standards
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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