| Risk of limb birth defects and mother's home proximity to cornfields. | |
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MedLine Citation:
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PMID: 19427676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although previous studies have linked proximity to crops and birth defects, they lacked individual-level exposure data and none was based on using planted area instead of linear proximity to crops as the exposure metric. We studied birth defects in relation to the area of corn or soybeans within 500 m of the mother's residence. METHODS: We selected all singleton births from rural areas conceived during the 2000-2004 spring-summer months (n=48,216). We determined whether the area with corn or soybeans around the home was associated with birth defects using multiple unconditional logistic regression. RESULTS: We found that limb birth defects (ICD-9-CM 754.5, 755) increased in relation to cornfields (Adjusted OR=1.22; 95 % CI=1.01, 1.47 per additional 10 ha planted with corn within 500 m). None of the birth defect types studied was associated with soybeans. CONCLUSIONS: In the Midwest, a significant and expanding proportion of the population is now living in close proximity to cornfields. Our results suggest that additional studies should be conducted to identify which factor(s) associated with cornfields are behind the observed increase in limb birth defects. |
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Authors:
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Hugo Ochoa-Acuña; Cristina Carbajo |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-05-08 |
Journal Detail:
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Title: The Science of the total environment Volume: 407 ISSN: 1879-1026 ISO Abbreviation: Sci. Total Environ. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-05 Completed Date: 2009-09-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0330500 Medline TA: Sci Total Environ Country: Netherlands |
Other Details:
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Languages: eng Pagination: 4447-51 Citation Subset: IM |
Affiliation:
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Epidemiology Section, Department of Comparative Pathobiology, Purdue University, 725 Harrison St, West Lafayette, IN 47907, USA. hochoaac@purdue.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Agriculture Cohort Studies Female Humans Indiana Limb Deformities, Congenital / epidemiology* Male Maternal Exposure* Pregnancy Risk Factors Zea mays* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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