Document Detail


Risk of limb birth defects and mother's home proximity to cornfields.
MedLine Citation:
PMID:  19427676     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although previous studies have linked proximity to crops and birth defects, they lacked individual-level exposure data and none was based on using planted area instead of linear proximity to crops as the exposure metric. We studied birth defects in relation to the area of corn or soybeans within 500 m of the mother's residence. METHODS: We selected all singleton births from rural areas conceived during the 2000-2004 spring-summer months (n=48,216). We determined whether the area with corn or soybeans around the home was associated with birth defects using multiple unconditional logistic regression. RESULTS: We found that limb birth defects (ICD-9-CM 754.5, 755) increased in relation to cornfields (Adjusted OR=1.22; 95 % CI=1.01, 1.47 per additional 10 ha planted with corn within 500 m). None of the birth defect types studied was associated with soybeans. CONCLUSIONS: In the Midwest, a significant and expanding proportion of the population is now living in close proximity to cornfields. Our results suggest that additional studies should be conducted to identify which factor(s) associated with cornfields are behind the observed increase in limb birth defects.
Authors:
Hugo Ochoa-Acuña; Cristina Carbajo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-08
Journal Detail:
Title:  The Science of the total environment     Volume:  407     ISSN:  1879-1026     ISO Abbreviation:  Sci. Total Environ.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-05     Completed Date:  2009-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0330500     Medline TA:  Sci Total Environ     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  4447-51     Citation Subset:  IM    
Affiliation:
Epidemiology Section, Department of Comparative Pathobiology, Purdue University, 725 Harrison St, West Lafayette, IN 47907, USA. hochoaac@purdue.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Agriculture
Cohort Studies
Female
Humans
Indiana
Limb Deformities, Congenital / epidemiology*
Male
Maternal Exposure*
Pregnancy
Risk Factors
Zea mays*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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