| Risk of heart failure relapse in subsequent pregnancy among peripartum cardiomyopathy mothers. | |
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MedLine Citation:
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PMID: 19945699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To quantify the level of risk for heart failure relapse in a subsequent pregnancy in women who have had peripartum cardiomyopathy (PPCM), and to test the hypothesis that meeting additional criteria may help lower the risk. METHODS: Prospectively-identified PPCM patients volunteering between 2003 and 2009 were identified from the PPCM Registry of H?pital Albert Schweitzer, Deschapelles, Haiti, and an internet support group. Data were assessed for full adherence to monitoring and diagnostic criteria, clinical data, statistical analysis, and reporting. RESULTS: Of 61 post-PPCM pregnancies identified, there were 18 relapses (29.5%) of heart failure. Of 26 pregnancies with a left ventricular ejection fraction (LVEF) of less than 0.55 prior to the pregnancy, relapse occurred in 12 (46.2%) pregnancies. Of 35 pregnancies with an LVEF of 0.55 or greater prior to the pregnancy, relapse occurred in 6 (17.1%) (P<0.01). No relapses occurred in 9 women who also demonstrated adequate contractile reserve. CONCLUSION: The most important criterion associated with reduced risk for heart failure relapse in a post-PPCM pregnancy is recovery defined by an LVEF 0.55 or greater before the subsequent pregnancy. Exercise stress echocardiography showing adequate contractile reserve may help to identify women at an even lower risk of relapse. |
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Authors:
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James D Fett; Karie L Fristoe; Serena N Welsh |
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Publication Detail:
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Type: Journal Article Date: 2009-11-30 |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 109 ISSN: 1879-3479 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-05-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: Ireland |
Other Details:
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Languages: eng Pagination: 34-6 Citation Subset: IM |
Copyright Information:
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Copyright 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Peripartum Cardiomyopathy Research Project, Department of Adult Medicine, H?pital Albert Schweitzer, Deschapelles, Haiti. fett.sprunger@comcast.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Haiti / epidemiology Heart Failure / diagnosis, epidemiology* Humans Pregnancy Pregnancy Complications, Cardiovascular / epidemiology* Prospective Studies Recurrence Risk Factors Stroke Volume United States / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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