Document Detail


Risk factors for thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study.
MedLine Citation:
PMID:  2183733     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
As previously reported, 1007 patients with chronic atrial fibrillation participated in the Copenhagen AFASAK study. Before inclusion to trial, they all had a physical examination, chest roentgenogram, and echocardiogram with determination of left atrial size. This study evaluated the importance of cardiovascular risk factors for development of thromboembolic complications. To exclude any treatment effects on occurrence of thromboembolic complications, we included only the 336 patients from the placebo group. Using Cox's regression model, previous myocardial infarction was a significant risk factor for development of thromboembolic complications. Age, gender, heart failure, chest pain, hypertensive heart disease, diabetes, systolic and diastolic blood pressure, smoking, relative heart volume, and left atrial size were all without statistical importance.
Authors:
P Petersen; J Kastrup; S Helweg-Larsen; G Boysen; J Godtfredsen
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of internal medicine     Volume:  150     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-05-14     Completed Date:  1990-05-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  819-21     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, University Hospital, Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aspirin / therapeutic use
Atrial Fibrillation / complications*
Denmark / epidemiology
Female
Humans
Male
Proportional Hazards Models
Randomized Controlled Trials as Topic
Regression Analysis
Risk Factors
Survival Rate
Thromboembolism / epidemiology*,  prevention & control
Warfarin / therapeutic use
Chemical
Reg. No./Substance:
50-78-2/Aspirin; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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