Document Detail

Risk factors for surgical site infections in neurosurgery patients with antibiotic prophylaxis.
MedLine Citation:
PMID:  15680644     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This prospective study aimed to determine the spectrum and the main risk factors of surgical site infection (SSI) after neurosurgical procedures in our clinic. METHODS: Consecutive patients undergoing neurosurgery between November 1, 2001, and November 1, 2002, were recruited for the study. All patients were followed for a minimum of 2 weeks postoperatively and all SSIs were recorded. The complete medical records of each case were reviewed, and data on 14 possible risk factors were extracted. Statistical analyses were performed to identify the risk factors for SSIs. RESULTS: A total of 31 postoperative SSIs were identified among 503 cases included in the study, with a resulting overall infection rate of 6.2%. The risk of SSI was increased by age (odds ratio [OR], 1.1; 95% confidence interval [CI], 1.0-1.1; P = .039), operation type such as "shunt operations" (OR, 670.4; 95% CI, 2.6-171123.1; P = .021), presence of foreign body (OR, 141.0; 95% CI, 2.5-7925.9; P = .016), presence of diabetes mellitus (OR, 24.3; 95% CI, 2.1-284.9; P = .011), and intracranial pressure monitoring (OR, 4878.9; 95% CI, 23.8-1001229; P = .002). The predominantly isolated microorganisms in patients with SSIs were Staphylococcus aureus (22 [71.0%]), Acinetobacter baumanii (5 [16.1%]), and Staphylococcus epidermidis (4 [12.9%]). CONCLUSIONS: SSIs remain an important problem in neurosurgery. Identification of the risk factors for SSI will help physicians to improve patient care and may decrease mortality, morbidity, and health care costs of neurosurgery patients.
Tahsin Erman; Hakan Demirhindi; A Iskender Göçer; Metin Tuna; Faruk Ildan; Bülent Boyar
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  63     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-31     Completed Date:  2005-03-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-12; discussion 112-3     Citation Subset:  IM    
Department of Neurosurgery, School of Medicine, Cukurova University, Balcali-Adana 01330, Turkey.
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MeSH Terms
Age Factors
Antibiotic Prophylaxis*
Logistic Models
Neurosurgical Procedures* / methods,  statistics & numerical data
Prospective Studies
Risk Factors
Surgical Wound Infection / epidemiology*
Turkey / epidemiology

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