| Risk factors for retrolental fibroplasia: experience with 3,025 premature infants. National Collaborative Study on Patent Ductus Arteriosus in Premature Infants. | |
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MedLine Citation:
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PMID: 2863804 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rate of retrolental fibroplasia in relation to prenatal and neonatal characteristics was explored on the basis of a cohort of 3,025 neonates with birth weight less than 1,750 g. The overall rate of retrolental fibroplasia of any degree at hospital discharge was 11%, varying from 43% for those with birth weight between 500 and 749 g to 3% for those in the 1,500- to 1,750-g category. Among the potential determinants, the main interest was in nonhyperoxic characteristics, conditional on measures of prematurity and oxygen supplementation. Maternal diabetes and antihistamine use during the last 2 weeks of pregnancy were associated with significantly higher rates of retrolental fibroplasia, whereas toxemia was associated with lower rates. Frequent apneic spells, bronchopulmonary dysplasia, and sepsis in the neonate were also associated with significantly higher rates. On the other hand, the data indicate no independent role of low Apgar score, intraventricular hemorrhage, exchange transfusion, patent ductus arteriosus, or certain other characteristics previously postulated as risk factors. |
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Authors:
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D M Purohit; R C Ellison; S Zierler; O S Miettinen; A S Nadas |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pediatrics Volume: 76 ISSN: 0031-4005 ISO Abbreviation: Pediatrics Publication Date: 1985 Sep |
Date Detail:
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Created Date: 1985-10-07 Completed Date: 1985-10-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 339-44 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia
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complications Apnea / complications Birth Weight Bronchopulmonary Dysplasia / complications Female Histamine H1 Antagonists / adverse effects Humans Infant, Low Birth Weight Infant, Newborn Infant, Premature, Diseases / epidemiology*, etiology Infection / complications Pre-Eclampsia / complications Pregnancy Pregnancy Complications, Hematologic Pregnancy in Diabetics / complications Retinopathy of Prematurity / epidemiology*, etiology Risk United States |
| Grant Support | |
ID/Acronym/Agency:
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HL23121/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Histamine H1 Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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