Document Detail

Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China.
MedLine Citation:
PMID:  18303154     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Guidelines on oxygenation policies and on the prevention and treatment of retinopathy of prematurity (ROP) were issued by the Chinese Medical Association in 2004. This study was undertaken to determine the incidence of and risk factors for ROP among preterm infants in Beijing, the capital of China, after implementation of the guidelines. METHODS: Neonates with birth weights (BW) < or = 2000 g or gestational age (GA) < or = 34 weeks admitted to the six largest neonatal intensive care units in Beijing during 2005 were enrolled. Ophthalmological examinations started 3-4 weeks after birth, and ROP was classified using the revised International Classification. Maternal and perinatal risk factors for type 1 ROP were analysed. RESULTS: Retinopathy of prematurity was detected in 10.8% of 639 neonates who had complete eye examinations, 23 of whom (3.6%) developed type 1 ROP and were treated. The rate of ROP needing treatment has not declined since 2002. Logistic regression analysis indicated that low BW, apnoea > 20 s, anaemia, hypoxic-ischaemic encephalopathy and placenta abruption were significantly associated with type 1 ROP. CONCLUSION: In Beijing, rates of ROP needing treatment are high, and affected babies are more mature than in NICUs in high-income countries. More needs to be done to prevent ROP through improved neonatal care.
Y Chen; X-x Li; H Yin; C Gilbert; J-h Liang; Y-r Jiang; M-w Zhao;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; Retracted Publication    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  92     ISSN:  1468-2079     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-27     Completed Date:  2008-03-14     Revised Date:  2008-08-14    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  326-30     Citation Subset:  IM    
Peking University People's Hospital, No. 11 Xi Zhi Men South Street, Beijing 100044, PR China.
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MeSH Terms
Abruptio Placentae
Anemia / complications
Apnea / complications
Birth Weight
China / epidemiology
Gestational Age
Hypoxia-Ischemia, Brain / complications
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Intensive Care Units, Neonatal / statistics & numerical data
Practice Guidelines as Topic
Retinopathy of Prematurity / epidemiology,  etiology*,  prevention & control
Risk Factors
Retraction In:
Br J Ophthalmol. 2008 Aug;92(8):1159   [PMID:  18668719 ]

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