| Risk factors for repeat syphilis in men who have sex with men, San Francisco. | |
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MedLine Citation:
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PMID: 19556925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Syphilis incidence has increased dramatically in the United States since 2000, occurring primarily among men who have sex with men (MSM) and disproportionately affecting those with human immunodeficiency virus (HIV) infection. The continued increases in syphilis rates among MSM signals the need for enhanced prevention methods. We undertook a study to examine the rate of repeat syphilis infection among MSM in San Francisco and to identify risk factors associated with syphilis reinfection that may inform additional prevention strategies. METHODS: We developed a retrospective cohort of all cases of primary, secondary, and early latent syphilis among MSM diagnosed in San Francisco in 2001 and 2002. We evaluated data through the end of 2003 to determine all cases of syphilis reinfection, defined as a new infection that occurred within 1 year after prior syphilis infection and treatment. RESULTS: We found that 6.7% (42/624) of cases had a repeat syphilis infection within 1 year. HIV infection was associated with an increased risk of repeat infection (OR = 4.7; CI, 1.8-12.0). No differences in age, race, number of period sex partners, illicit substance use, or partner meeting venues were observed between cases with and without repeat infection. CONCLUSIONS: Our study revealed that HIV-infected MSM with syphilis represent an at-risk group for repeat syphilis infection. Targeting increased screening and risk reduction interventions to HIV-infected MSM in care could reduce the overall incidence of syphilis among MSM. |
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Authors:
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Warren Phipps; Charlotte K Kent; Robert Kohn; Jeffrey D Klausner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Sexually transmitted diseases Volume: 36 ISSN: 1537-4521 ISO Abbreviation: Sex Transm Dis Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-26 Completed Date: 2009-10-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705941 Medline TA: Sex Transm Dis Country: United States |
Other Details:
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Languages: eng Pagination: 331-5 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Washington, Virology Research Center, 600 Broadway, Suite 400, Seattle, WA 98122, USA. wphipps@u.washington.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies HIV Infections / complications* Homosexuality, Male* Humans Incidence Male Retrospective Studies Risk Factors San Francisco / epidemiology Syphilis / complications, epidemiology* |
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