Document Detail

Risk factors for recurrent sinus surgery in cystic fibrosis: review of a decade of experience.
MedLine Citation:
PMID:  17882919     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patients with cystic fibrosis (CF) who undergo endoscopic sinus surgery often require multiple revision procedures. Our objective was to identify risk factors for revision sinus surgery in patients with CF, to better identify this subset of patients who might be better suited for alternative interventions at their initial procedure. METHODS: Patients with CF who presented to our academic tertiary care sinus clinic between 1994 and 2003 were reviewed. Data were collected from CT scans using the Lund-Mackay scale. Data are collected on demographics, comorbidities, CF genotype, number and type of sinus surgeries, and pulmonary function tests. RESULTS: Eighty-one patients met inclusion criteria. Fifty patients were <18 years old at presentation. Forty-one patients were A508 homozygotes, 32 patients were A508 heterozygotes, and 5 patients were non-A508 heterozygotes. Respiratory comorbidities were asthma alone (28%) and aspirin triad (5%). Eighteen (22%) patients either smoked or lived with smokers. The mean Lund-Mackay score before the initial surgery was 16. Twenty patients were treated with medication only; 35 patients underwent 1 surgery; 14 patients underwent 2 surgeries; 8 patients underwent 3 surgeries; 2 patients underwent 4 surgeries; and 2 patients underwent 5 surgeries. Patients with higher Lund-Mackay scores at their initial CT were more likely to undergo repeat surgeries (p < 0.05). CONCLUSION: CF patients with high Lund-Mackay scores at their initial surgery are more likely to undergo several revision surgeries. These patients should be considered for more alternative initial management of their sinuses.
Samuel S Becker; Alessandro de Alarcon; Steven R Bomeli; Joseph K Han; Charles W Gross
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  21     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-09-21     Completed Date:  2007-11-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  478-82     Citation Subset:  IM    
University of Virginia Health System, Department of Otolaryngology and Head and Neck Surgery, Charlottesville, Virginia 22908-0713, USA.
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MeSH Terms
Child, Preschool
Cystic Fibrosis / epidemiology*
Middle Aged
Retrospective Studies
Risk Assessment
Risk Factors
Sinusitis / epidemiology*,  surgery*

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