Document Detail

Risk factors of preterm delivery at less than 35 weeks in patients with renal transplant.
MedLine Citation:
PMID:  16377066     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To identify prenatal events associated with preterm delivery at less than 35 weeks of gestation in women with renal transplant. METHODS: A case-control study of 53 pregnancies in 42 renal transplant recipients, at a single center from 1984 to 2003 was analyzed. Preterm delivery cases (n=23) at less than 35 weeks of gestation were compared with the controls (n=30). RESULTS: Preterm delivery at less than 35 weeks of gestation occurred in 23 cases (43.4%). Hypertension (> or =140/90 mmHg) prior to pregnancy (odds ratio (OR) 6.3, 95% confidence interval (CI) 1.0-38.6), proteinuria (> or =0.3g/day) prior to delivery (OR 11.7, CI 2.7-51.8) and serum creatinine (> or =1.5mg/dl) prior to delivery (OR 4.4, CI 1.0-19.5) were significantly associated with increased risk of preterm delivery. Perinatal or neonatal deaths were not found. Fetal anomaly was seen in one case (polydactyly), and periventricular leukomalacia was found in two cases. CONCLUSION: In this case-control study, hypertension prior to pregnancy, proteinuria and serum creatinine (> or =1.5mg/dl) prior to delivery were related to the occurrence of preterm delivery at less than 35 weeks in renal transplant pregnancies.
Akiko Kurata; Yoshio Matsuda; Kazunari Tanabe; Hiroshi Toma; Hiroaki Ohta
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Publication Detail:
Type:  Journal Article     Date:  2005-12-22
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  128     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-09-11     Completed Date:  2007-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  64-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Tokyo Women's Medical University Kawada-cho, 8-1 Shinjuku-ku, Tokyo 162-8666, Japan.
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MeSH Terms
Creatinine / blood
Hypertension / complications*
Infant, Low Birth Weight
Infant, Newborn
Kidney Transplantation / adverse effects*
Premature Birth / etiology*
Proteinuria / complications
Retrospective Studies
Risk Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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