| Risk factors for pancreas-related abscess after total gastrectomy. | |
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MedLine Citation:
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PMID: 16086115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: European clinical trials of gastrectomy have shown that pancreas-related complications are the major cause of mortality. The aim of this study was to determine the risk factors for pancreas-related abscess after gastrectomy and to evaluate the effects of the abscess on postoperative mortality. METHODS: Between 1992 and 1999, 663 consecutive patients with gastric carcinoma underwent total gastrectomy. Data from these patients were analyzed, to identify the predictors of pancreas-related abscess caused by pancreatic juice leakage, by a multiple logistic regression model. RESULTS: On multivariate analysis, increasing age (P = 0.018) and body mass index (P = 0.006) were independent preoperative risk factors. Dissection along the distal splenic artery was an intraoperative risk factor. The hazard ratios were increased 9.13-fold (P = 0.000) with a pancreas-preserving operation and 16.72-fold (P = 0.000) by distal pancreatectomy. Patients with the abscess had a higher postoperative mortality rate (P = 0.008), and a higher re-operation rate (P < 0.001) than patients without the abscess. CONCLUSION: Pancreas-related abscess is more likely to occur in older, obese patients undergoing node dissection along the distal splenic artery. Abscess formation is associated with a higher mortality and re-operation rate. Spleen preservation should be evaluated in Japan. |
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Authors:
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Hitoshi Katai; Kimio Yoshimura; Takeo Fukagawa; Takeshi Sano; Mitsuru Sasako |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association Volume: 8 ISSN: 1436-3291 ISO Abbreviation: Gastric Cancer Publication Date: 2005 |
Date Detail:
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Created Date: 2005-08-08 Completed Date: 2005-11-22 Revised Date: 2007-01-08 |
Medline Journal Info:
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Nlm Unique ID: 100886238 Medline TA: Gastric Cancer Country: Japan |
Other Details:
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Languages: eng Pagination: 137-41 Citation Subset: IM |
Affiliation:
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Department of Surgical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abscess
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etiology*,
mortality Adult Aged Aged, 80 and over Female Gastrectomy / adverse effects* Humans Japan / epidemiology Male Middle Aged Pancreatic Diseases / etiology*, mortality Postoperative Complications* Risk Factors Splenectomy Stomach Neoplasms / surgery Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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