Document Detail


Risk factors of neurologic deficit after thoracic aortic endografting.
MedLine Citation:
PMID:  17257946     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Stroke and spinal cord injury (SCI) remain the most devastating complications of thoracic endovascular aortic repair (TEVAR). The risk factors associated with these complications are poorly understood. The aim of this study was to analyze the risk factors associated with neurologic deficits after TEVAR. METHODS: From 1998 to 2005, 153 patients underwent 184 TEVARs. Computed tomography scans, angiograms, and medical records were reviewed. TEVAR was completed in all but 3 patients. The underlying pathologies included descending thoracic aortic aneurysm in 91, acute type B aortic dissection in 25, chronic type B aortic dissection in 42, aortic transection in 12, and penetrating aortic ulcer in 14. RESULTS: Stroke developed in 8 patients, and SCI developed in another 8 patients (4 immediate, 4 delayed paraplegia/paraparesis). The procedure-associated stroke and SCI rate was 4.3% (8/184). Univariate statistical analysis revealed increased postoperative stroke with obesity, significant intraoperative blood loss, and evidence of peripheral vascular embolization/thrombosis. Aneurysmal pathology, iliac conduit, and hypogastric artery coverage were highly associated with postoperative SCI after TEVAR. Early and late mortality were 9.8% (n = 18) and 19% (n = 35) in a 16-month average period of follow-up. CONCLUSIONS: The incidence of stroke and SCI after TEVAR was 4.3% (8/184). The risk factors associated with postoperative stroke were obesity, intraoperative blood loss, and vascular embolization. Aneurysm as an underlying pathology, the use of an iliac conduit, and coverage of the hypogastric artery were all associated with SCI. These risk factors for SCI may be markers of tenuous collateral blood supply to the spinal cord.
Authors:
Ali Khoynezhad; Carlos E Donayre; Hao Bui; George E Kopchok; Irwin Walot; Rodney A White
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  83     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-29     Completed Date:  2007-03-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  S882-9; discussion S890-2     Citation Subset:  AIM; IM    
Affiliation:
Section of Cardiovascular and Thoracic Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198-2315, USA. akhoynezhad@unmc.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aneurysm, Dissecting / surgery
Aorta, Thoracic / injuries,  surgery*
Aortic Aneurysm, Thoracic / surgery
Aortic Diseases / complications,  surgery*
Blood Loss, Surgical
Blood Vessel Prosthesis Implantation / adverse effects*,  methods*
Embolization, Therapeutic / adverse effects
Female
Humans
Male
Middle Aged
Obesity / complications
Risk Factors
Spinal Cord Injuries / etiology*
Stroke / etiology*
Ulcer / surgery
Wounds, Penetrating / complications,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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