Document Detail


Risk factors in early-onset neonatal group b streptococcal infections.
MedLine Citation:
PMID:  348607     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Newborn infants with "early-onset" disease due to group B beta hemolytic streptococcus were studied over a 40-month period. Clinical presentations included asymptomatic bacteremia, mild transient illness, respiratory distress, meningitis, and overwhelming sepsis. Chronologically, 18 were ill at birth; 10 became ill after a symptom-free period; and four were asymptomatic. Sixty-six percent of the cases weighted less than 2500 grams, and 56% were born to mothers whose amniotic membranes were ruptured for over 20 hours. All 15 of the deaths occurred in low birth weight infants who were criticially ill from birth. A review of 128 consecutive deliveries of infants weighing under 2000 grams revealed 28 cases with prolonged ruptured membranes, and three of these 28 infants developed group B streptococcal infection. The infant of the colonized gravid woman in premature labor or with prolonged ruptured membranes is clearly at risk, and these results suggest that the management of "early-onset" disease should begin prior to delivery.
Authors:
P B Stewardson-Krieger; S P Gotoff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infection     Volume:  6     ISSN:  0300-8126     ISO Abbreviation:  Infection     Publication Date:  1978  
Date Detail:
Created Date:  1978-07-15     Completed Date:  1978-07-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365307     Medline TA:  Infection     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  50-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Membranes, Premature Rupture*
Fever / complications
Humans
Infant, Low Birth Weight
Infant, Newborn
Infant, Newborn, Diseases*
Pregnancy
Puerperal Infection / complications
Streptococcal Infections*
Streptococcus agalactiae / isolation & purification

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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