Document Detail


Risk factors in early life as predictors of adult heart disease: the Bogalusa Heart Study.
MedLine Citation:
PMID:  2679086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The adult heart diseases, coronary artery disease and essential hypertension, are now clearly recognized to begin in childhood. The evidence comes from autopsy studies of cardiovascular-renal changes in the first two decades of life. Cardiovascular risk factors can be identified in children just as in adults and these have a high correlation with the anatomic disease. This relationship underscores the importance of risk factor screening of children. Of interest is that clinical risk factors tend to persist within a rank (track) so that studies in childhood can be predictive of future levels. Behavior and lifestyle of eating, cigarette smoking, alcohol intake, and use of oral contraceptive pills influence risk factors in children. Familial aggregation of risk factors are also noted. Studies of apolipoproteins, B and A-I, have identified subsets of children that have a greater frequency of paternal myocardial infarction. The findings from the Bogalusa Heart Study and other epidemiological studies of children show the need to begin prevention of adult heart disease in early life. Approaches to prevention should include high risk families and children and a public health or population approach. Cardiovascular health education for elementary school children should be directed to children in the general population in an effort to encourage them to adopt healthy life styles.
Authors:
G S Berenson; S R Srinivasan; S M Hunter; T A Nicklas; D S Freedman; C L Shear; L S Webber
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  298     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-10-31     Completed Date:  1989-10-31     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  141-51     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Louisiana State University Medical Center, New Orleans 70112-2228.
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MeSH Terms
Descriptor/Qualifier:
Aging / physiology
Apolipoproteins / blood
Behavior / physiology
Blood Pressure
Continental Population Groups
Heart Diseases / etiology*,  prevention & control
Humans
Life Style
Lipids / blood,  genetics
Lipoproteins / blood
Risk Factors
Sex Characteristics
Somatotypes
Grant Support
ID/Acronym/Agency:
HL-15103/HL/NHLBI NIH HHS; HL-38844/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Apolipoproteins; 0/Lipids; 0/Lipoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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