Document Detail


Risk factors in the development of multiple sclerosis.
MedLine Citation:
PMID:  20477024     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Multiple sclerosis (MS) is a T-cell-mediated demyelinating disease of the CNS with no known cure or cause. However, it is widely believed that MS is caused by an environmental trigger(s) in genetically susceptible individuals. Several lines of evidence suggest that infection with Epstein-Barr virus and cigarette smoking increase the risk of MS, whereas vitamin D plays a protective role. This review discusses the current evidence supporting a link between these factors and MS.
Authors:
Kassandra L Munger; Alberto Ascherio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of clinical immunology     Volume:  3     ISSN:  1744-8409     ISO Abbreviation:  Expert Rev Clin Immunol     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101271248     Medline TA:  Expert Rev Clin Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  739-48     Citation Subset:  -    
Affiliation:
Harvard School of Public Health, Department of Nutrition, 655 Huntington Ave, Boston, MA 02115, USA. kgorham@hsph.harvard.edu
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