Document Detail

Risk factors for hypertension in chronic hemodialysis patients: baseline data from the HEMO study.
MedLine Citation:
PMID:  11509799     Owner:  NLM     Status:  MEDLINE    
A cross-sectional analysis was performed to determine risk factors associated with hypertension in 1,238 chronic hemodialysis patients upon enrollment into the HEMO Study. The mean pre- and post-dialysis systolic blood pressure were 152.4 +/- 25.0 (mean +/- SD) and 137.8 +/- 24.6 mm Hg, respectively. The mean pre- and post-dialysis diastolic blood pressures were 82.1 +/- 14.8 and 74.7 +/- 13.8 mm Hg, respectively. Less than 30% of the study cohort had blood pressures that were normotensive by JNC VI guidelines. Risk factors associated with higher pre- and post-dialysis systolic blood pressures included the presence of diabetes mellitus, older age, increased number of prescribed antihypertensive medications, lower hematocrit, and absence of arrhythmias. Variables associated with higher pre- and post-dialysis diastolic blood pressures included younger age, increased number of prescribed anti-hypertensive medications and absence of arrhythmias. There was also a nonlinear relationship between blood pressure and prescribed total ultrafiltration volume. A total ultrafiltration volume of >2.5 kg was associated with an elevation in pre-dialysis systolic and diastolic blood pressures. A total ultrafiltration volume of < or =2.5 kg was associated with an elevation in post-dialysis systolic and diastolic blood pressures. These data on ultrafiltration volume suggest that higher pre-dialysis blood pressures may be associated with excessive interdialytic weight gains due to patient noncompliance with fluid restriction and that higher post-dialysis blood pressures may be associated with a prescribed dry weight that is higher than the patient's true dry weight. Better management of these parameters may improve the prevalence and severity of hypertension in this population.
M V Rocco; G Yan; R J Heyka; R Benz; A K Cheung;
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of nephrology     Volume:  21     ISSN:  0250-8095     ISO Abbreviation:  Am. J. Nephrol.     Publication Date:    2001 Jul-Aug
Date Detail:
Created Date:  2001-08-17     Completed Date:  2001-10-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8109361     Medline TA:  Am J Nephrol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  280-8     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1053, USA.
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MeSH Terms
Clinical Trials as Topic
Cross-Sectional Studies
Hypertension / epidemiology*
Kidney Failure, Chronic / etiology,  therapy
Middle Aged
Multicenter Studies as Topic
Renal Dialysis*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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