| Risk factors for early sepsis in very low birth weight neonates with respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 18052996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To identify maternal and neonatal factors that increase suspicion of early sepsis in Very Low Birth Weight neonates with respiratory distress syndrome. METHODS: The cohort included 282 neonates born at Soroka Medical Centre 1996-2000. Definitions of 'high' and 'low'-suspicion groups for early sepsis were based on comparison between neonates with early sepsis and the remaining cohort. Univariate analysis and logistic regression were used to compare between groups. RESULTS: The incidence of early sepsis in the cohort was 1.8%, and 94% received antibiotics following delivery. Comparing with the remaining cohort, the five neonates with early sepsis had increased incidence of positive maternal cultures, use of antenatal antibiotics, lower 1 min Apgar scores and tendency to leucopenia. A 'low-suspicion' group comprised 38% of the cohort and did not include any neonates with early sepsis. This group were more frequently treated with antenatal steroids and delivered by Caesarean section compared to the 'high-suspicion' group, but otherwise there were no clinical and laboratory differences. CONCLUSION: Although the incidence of early sepsis is low almost all neonates received antibiotics. A 'low-suspicion' group was defined and the role of antibiotic treatment in this group needs to be determined. |
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Authors:
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Laliv Shani; Dahlia Weitzman; Rimma Melamed; Ehud Zmora; Kyla Marks |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2007-12-03 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 97 ISSN: 0803-5253 ISO Abbreviation: Acta Paediatr. Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-18 Completed Date: 2008-04-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 12-5 Citation Subset: IM |
Affiliation:
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Faculty of Health Science, Ben Gurion University, Beer Sheva, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cohort Studies Female Humans Incidence Infant, Newborn Infant, Very Low Birth Weight Male Respiratory Distress Syndrome, Newborn / complications* Risk Factors Sepsis / complications*, epidemiology* |
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