Document Detail

Risk factors for early post-operative psychiatric symptoms in patients undergoing epilepsy surgery for temporal lobe epilepsy.
MedLine Citation:
PMID:  19486325     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: De-novo psychiatric symptoms may develop within 3 months after a temporal lobectomy for epilepsy. The objective of this study was to identify presurgical risk factors for psychiatric symptoms. METHODS: Twenty-seven patients who had a temporal lobectomy for epilepsy were included. Twenty-four had hippocampal sclerosis or gliosis, and three had cavernous haemagiomata. Twelve had operations on the left, and 15 on the right side. Twenty-four patients were rendered free of seizures (SZ) with loss of awareness, three had early post-operative convulsions, one continued to have habitual SZ. RESULTS: Nine patients (33%) developed low mood, anxiety and emotional lability within 3 months after surgery. Patients with early post-operative psychiatric symptoms were younger (27.9/34.8 years, P = 0.01), and more anxious on the presurgical Hospital Anxiety and Depression Scale (12/8.44, P = 0.02) than patients without post-operative psychiatric symptoms. There was also an association between right temporal lobectomies and early post-surgical symptoms (P = 0.02 Fisher's exact test). CONCLUSION: Potential risk factors were age, anxiety and operation on the right side. Larger studies are required to determine if these risk factors are independent.
K Moss; K O'Driscoll; P Eldridge; T Varma; U C Wieshmann
Related Documents :
24139555 - Obesity, outcomes and quality of care: body mass index increases the risk of wound-rela...
24259355 - Beyond the operating room: a look at legal liability in body contouring procedures.
6698325 - Long-term outcome in children with temporal lobe seizures. v: indications and contra-in...
16736735 - Morbidity associated with the use of intracranial electrodes for epilepsy surgery.
23914605 - Early rehabilitative treatment in aortocoronary bypass surgery.
8918055 - Surgical treatment of peptic ulcer disease: changing patterns in the past 40 years.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  120     ISSN:  1600-0404     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-01     Completed Date:  2009-10-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  176-81     Citation Subset:  IM    
Department of Neurology, Liverpool, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Affective Symptoms / etiology*
Anterior Temporal Lobectomy / psychology*
Epilepsy, Temporal Lobe / surgery*
Middle Aged
Postoperative Period
Risk Assessment
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vascular cognitive syndromes: relation to stroke etiology and topography.
Next Document:  Morphological and immunohistochemical characterization of paraneoplastic cerebellar degeneration ass...