Document Detail

Risk factors for death and changing patterns in leptospirosis acute renal failure.
MedLine Citation:
PMID:  10548299     Owner:  NLM     Status:  MEDLINE    
The risk factors for death and changes in clinical patterns in leptospirosis (Weil's disease) have not been well studied. We retrospectively studied 110 patients with Weil's disease hospitalized in Brazil between 1985 and 1996. Univariate statistical analysis showed that nonsurvivors were older than survivors, and had higher frequency of oliguria, cardiac arrhythmia, dyspnea, and pulmonary rales. Logistic regression showed that the only independent factor associated with death was oliguria (odds ratio [OR] = 8.98). The presence of arthralgia (OR = 4.71), dehydration (OR = 6.26), dyspnea (OR = 17.7), and pulmonary rales (OR = 9.91) increased after 1994. These data suggest that in Weil's disease the clinical patterns have changed and the presence of oliguria is a risk factor for death.
E Daher; D M Zanetta; M B Cavalcante; R C Abdulkader
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  61     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-16     Completed Date:  1999-11-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  630-4     Citation Subset:  AIM; IM    
Departamento de Medicina Clínica, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
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MeSH Terms
Age Factors
Aged, 80 and over
Arrhythmias, Cardiac / physiopathology
Blood Pressure
Dyspnea / physiopathology
Kidney Failure, Acute / mortality*,  physiopathology
Leptospira / pathogenicity*
Middle Aged
Oliguria / physiopathology
Respiratory Sounds / physiopathology
Retrospective Studies
Risk Factors
Sex Factors
Weil Disease / mortality*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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