| Risk factors and clinical course of portal and/or splenic vein thrombosis after partial splenic embolization. | |
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MedLine Citation:
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PMID: 19449229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although portal and/or splenic vein thrombosis after partial splenic embolization (PSE) is a well-known complication, few reports evaluating risk factors have been published. PURPOSE: To investigate risk factors and clinical course of portal and/or splenic vein thrombosis after PSE. MATERIAL AND METHODS: Sixteen patients with severe hypersplenism underwent PSE between March 2005 and April 2008. The correlation between portal and/or splenic vein thrombosis after PSE detected on multidetector row CT (MDCT) and various factors were retrospectively reviewed. Further, the clinical course of portal and/or splenic vein thrombosis after PSE was observed on follow-up MDCT. RESULTS: Splenic vein thrombosis was detected in eight patients (50%) on MDCT images taken within 9 days after PSE. In one, the thrombosis also involved the portal vein. The infarct volume was identified as a significant risk factor for portal and/or splenic vein thrombosis (P=0.046). In all but one patient, splenic vein thrombosis resolved completely or improved without anticoagulation therapy. In this patient, both portal and splenic vein thrombosis developed after PSE, and anticoagulation therapy was necessary. CONCLUSION: It is suggested that a large splenic infarct volume is a risk factor for portal and/or splenic vein thrombosis after PSE. Indications for treatment of thrombosis of the portal vein system after PSE may be limited to patients with portal vein thrombosis. |
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Authors:
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Tomohiro Matsumoto; Takuji Yamagami; Koshi Terayama; Takeharu Kato; Tatsuya Hirota; Rika Yoshimatsu; Hiroshi Miura; Hirotoshi Ito; Takeshi Okanoue; Tsunehiko Nishimura |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 50 ISSN: 1600-0455 ISO Abbreviation: Acta Radiol Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-23 Completed Date: 2009-07-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: England |
Other Details:
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Languages: eng Pagination: 617-23 Citation Subset: IM |
Affiliation:
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Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto, Japan. t-matsu@koto.kpu-m.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Contrast Media / diagnostic use Embolization, Therapeutic / adverse effects, methods* Female Humans Hypersplenism / therapy* Male Middle Aged Observer Variation Portal Vein / radiography* Radiographic Image Enhancement / methods Retrospective Studies Risk Factors Splenic Vein / radiography* Tomography, X-Ray Computed / methods Treatment Outcome Venous Thrombosis / diagnosis*, etiology, radiography |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
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