| Risk factors for cervical presence of human papillomavirus DNA among women at risk for HIV infection. DIANAIDS Collaborative Study Group. | |
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MedLine Citation:
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PMID: 9747769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Risk factors for cervical infection with human papillomavirus (HPV) were assessed among 236 Italian women at risk for human immunodeficiency virus (HIV) infection (intravenous drug users (IVDU) or sexual partners of males at risk for HIV infection). All study participants underwent a structured interview, determination of HIV serostatus and detection of HPV cervical infection by means of polymerase chain reaction (PCR). Overall, the cervical presence of HPV DNA was ascertained in 86 of these 236 women (36.4%), while squamous intraepithelial lesions (SIL) were diagnosed in 57 (24.1%). HPV-infected and non-infected women did not differ in age, education and cigarette smoking. A statistically significant trend in the risk of HPV infection with increasing number of lifetime sexual partners was noted (P = 0.01), but such trend was attenuated in multivariate analysis (multiple logistic regression (MLR) odds ratio (OR) for > or = 20 partners vs 1 = 1.6, 95% confidence intervals (CI): 0.4-5.9). A nearly threefold higher risk of HPV cervical infection emerged among IVDU women (MLR-OR: 2.7, 95% CI: 1.4-5.0), and this difference was not influenced by HIV serostatus. The prevalence of HIV infection was higher among HPV-positive than HPV-negative women (62.8% and 54.0%, respectively) (MLR-OR = 1.9, 95% CI: 0.9-3.8), and the proportion of women with less than 200 CD4+ cells/mm3 was slightly and not significantly higher among HPV-positive (47.1%) than negative women (37.2%). |
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Authors:
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G Rezza; M Giuliani; D Serraino; M Branca; A Benedetto; A Garbuglia; G Ippolito; S Franceschi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Epidemiology and infection Volume: 121 ISSN: 0950-2688 ISO Abbreviation: Epidemiol. Infect. Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-09-29 Completed Date: 1998-09-29 Revised Date: 2010-03-03 |
Medline Journal Info:
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Nlm Unique ID: 8703737 Medline TA: Epidemiol Infect Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 173-7 Citation Subset: IM; X |
Affiliation:
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Centro Operativo AIDS, Istituto Superiore di Sanit?, Roma, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA, Viral
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analysis Female HIV Infections / epidemiology* Humans Italy Logistic Models Papillomaviridae / isolation & purification* Papillomavirus Infections / epidemiology* Prevalence Prospective Studies Risk Factors Tumor Virus Infections / epidemiology* Uterine Cervical Diseases / epidemiology*, virology |
| Chemical | |
Reg. No./Substance:
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0/DNA, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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