Document Detail

Risk factors for cardiovascular hospitalization in hemodialysis patients.
MedLine Citation:
PMID:  20966631     Owner:  NLM     Status:  MEDLINE    
MATERIALS AND METHODS: A cross-sectional cohort analysis of risk factors during one census month (November) and one-year follow-up for cardiovascular hospitalization rates during 5 consecutive years (2002-2006) in all end-stage renal disease patients hemodialyzed in Kaunas region was carried out. During the census month, we collected data on patient's age and sex, disability status, comorbidities, anemia control, malnutrition and inflammation, calcium-phosphorus metabolism, and patient's compliance with prescribed medications. We analyzed 559 patients during 1163 patient-years of observation. Patients were considered as new patients every year (1520 cases). Kaplan-Meier method and Cox regression analysis were used to evaluate time to first hospitalization.
RESULTS: The mean number of cardiovascular hospitalizations was 0.31 per patient-year at risk, the total days of cardiovascular hospitalizations per patient-year at risk were 3.93, and the mean length of one hospitalization was 13.2±12.9 days. Cardiovascular diseases were the most frequent cause of hospitalization (25% of all hospitalizations). The relative risk of cardiovascular hospitalization increased by 1.03 for every year of age, by 1.7 for worse disability status, by 1.4 for nonadherence to medications, by 1.1 for every additional medication prescribed to the patient. Cardiovascular hospitalization risk was decreased by 0.99 with a 1-g/L rise in hemoglobin level.
CONCLUSIONS: Older age, worse disability status, patient's noncompliance with medications, and higher number of medications used were associated with a higher risk for cardiovascular hospitalization. Higher hemoglobin level was associated with a lower risk for cardiovascular hospitalization.
Rūta Vaičiūnienė; Vytautas Kuzminskis; Edita Ziginskienė; Kristina Petrulienė
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Medicina (Kaunas, Lithuania)     Volume:  46     ISSN:  1648-9144     ISO Abbreviation:  Medicina (Kaunas)     Publication Date:  2010  
Date Detail:
Created Date:  2010-10-22     Completed Date:  2010-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9425208     Medline TA:  Medicina (Kaunas)     Country:  Lithuania    
Other Details:
Languages:  eng     Pagination:  544-9     Citation Subset:  IM    
Department of Nephrology, Kaunas University of Medicine, Eivenių 2, 50028 Kaunas, Lithuania.
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MeSH Terms
Age Factors
Cardiovascular Diseases / blood,  epidemiology*
Cohort Studies
Cross-Sectional Studies
Data Interpretation, Statistical
Disabled Persons
Length of Stay
Medication Adherence
Middle Aged
Patient Compliance
Renal Dialysis*
Risk Factors
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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