| Risk factors for cardiovascular disease and endothelin-1 levels in Takayasu arteritis patients. | |
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MedLine Citation:
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PMID: 19057845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of this study was to evaluate traditional risk factors for cardiovascular disease (CVD) and endothelin-1 (ET-1) levels in Takayasu arteritis (TA) patients. Twenty-two TA patients and 37 controls were evaluated. TA patients had a higher prevalence of hypertension (63.6% vs. 21.6%, p=0.001) and higher levels of triglycerides (129.5 mg/dL+/-70.8 vs. 88.4 mg/dL+/-60.8, p=0.017) than controls. Mean number of CVD risk factors was 1.64+/-1.22 in TA patients and 1.03+/-1.44 among controls, p=0.030. More TA patients presented at least one CVD risk factor when compared to controls (77.2% vs. 51.3%, p=0.048). ET-1 levels were higher in patients than in controls (1.49 pg/mL+/-0.45 vs. 1.27 pg/mL+/-0.32, p=0.034), however no significant difference was found between patients with active and inactive disease. In this study, TA patients presented a higher prevalence of hypertension, higher levels of triglycerides, and ET-1 than controls. |
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Authors:
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Alexandre Wagner Silva de Souza; Henrique Ataíde Mariz; Edgard Torres Reis Neto; Anne Elizabeth Diniz Arraes; Neusa Pereira da Silva; Emília Inoue Sato |
Publication Detail:
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Type: Journal Article Date: 2008-12-05 |
Journal Detail:
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Title: Clinical rheumatology Volume: 28 ISSN: 1434-9949 ISO Abbreviation: Clin. Rheumatol. Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-02-26 Completed Date: 2009-08-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: Germany |
Other Details:
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Languages: eng Pagination: 379-83 Citation Subset: IM |
Affiliation:
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Rheumatology Division, Universidade Federal de São Paulo, Rua Botucatu, 740, 04023-900 São Paulo, SP, Brazil. alexandre_wagner@uol.com.br |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atherosclerosis / blood, complications, diagnosis Cardiovascular Diseases / blood*, complications*, diagnosis Endothelin-1 / blood* Female Humans Hypertension / blood Inflammation Male Middle Aged Risk Factors Takayasu Arteritis / blood*, complications*, diagnosis Treatment Outcome Triglycerides / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Endothelin-1; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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