Document Detail

Risk factors associated with preterm birth according to gestational age at birth.
MedLine Citation:
PMID:  18327870     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS: Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respectively in the three case-control analyses. Women were categorized according to whether they carried single or multiple infants. RESULTS: Obstetrical conditions (placenta previa, placental abruption), and maternal hypertension were significantly associated with preterm delivery in all case-control analyses (adjusted OR between 1.34-19.56, p < 0.05). Leading risk factors for preterm delivery in singleton pregnancies were placental abruption and placenta previa (adjusted ORs 4.85 and 4.13, p < 0.05). For multiple pregnancies they were polyhydramnios and maternal hypertension (adjusted ORs 4.39 and 2.45, p < 0.05). CONCLUSIONS: Obstetrical conditions during the pregnancy and maternal hypertension are important risk factors for preterm birth.
Benjamin D Ofori; Magali Le Tiec; Anick Bérard
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pharmacoepidemiology and drug safety     Volume:  17     ISSN:  1099-1557     ISO Abbreviation:  Pharmacoepidemiol Drug Saf     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-03     Completed Date:  2008-07-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9208369     Medline TA:  Pharmacoepidemiol Drug Saf     Country:  England    
Other Details:
Languages:  eng     Pagination:  556-64     Citation Subset:  IM    
Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada.
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MeSH Terms
Abruptio Placentae / epidemiology
Case-Control Studies
Databases, Factual
Gestational Age*
Hypertension, Pregnancy-Induced / epidemiology
Odds Ratio
Placenta Previa / epidemiology
Polyhydramnios / epidemiology
Pregnancy, Multiple
Premature Birth / epidemiology,  etiology*
Quebec / epidemiology
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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