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Risk factors associated to clinical deterioration during the transport of sick newborn infants.
MedLine Citation:
PMID:  22859323     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Adequate neonatal transport is a key component in the care of newborn infants that require transfer. Objective. To determine the characteristics and risk of clinical deterioration during neonatal transport. Material and Methods. This was an observational and prospective study that consecutively included newborn infants transferred to the Neonatal Intensive Care Unit (NICU) of the Hospital Garrahan. The TRIPS (Transport Risk Index of Physiology Stability) risk score was measured pre- and post-transport. A diagnosis of clinical deterioration was made when the post-transport TRIPS score was higher than the pre-transport score. Newborns characteristics, transport distance, newborns status upon admission, need for immediate cardiorespiratory support (ICRS), and death before the 7th day and at discharge were recorded. Bivariate and multivariate analyses were used to assess the associations with clinical deterioration . Results. A total of 160 transferred newborn infants were enrolled, gestational age (GA) was 35 ± 3 weeks; birth weight (BW) 2482 ± 904 g and median age 2 days. Most were referred due to cardiorespiratory (50%) or surgical (34%) illnesses. Of them, 91 (57%) had clinical deterioration and 46% hypothermia. Forty nine neonates required ICRS and 28 died (twelve before 7 days after admittance). Variables assessed were not associated with the risk of clinical deterioration. Mortality was higher in the group with clinical deterioration (OR: 3.34; 95% CI: 1.2-8.7), even when severity of the clinical picture was considered (OR A: 3; 95% CI: 1.2-8.3). Clinical deterioration during transport was associated with the need for ICRS (OR: 2.4; 95% CI: 1.2-5). Conclusions. In our experience transferred newborn infants often suffered loss of stability or clinical deterioration, regardless of their characteristics, and this was related to a higher mortality. Therefore, it is critical to optimize care strategies during all neonatal transports.
Authors:
Gustavo Goldsmit; Cecilia Rabasa; Susana Rodríguez; Yanina Aguirre; Martín Valdés; Damián Pretz; Daniela Carmona; Susana López Tornow; Diana Fariña
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archivos argentinos de pediatría     Volume:  110     ISSN:  1668-3501     ISO Abbreviation:  Arch Argent Pediatr     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372460     Medline TA:  Arch Argent Pediatr     Country:  Argentina    
Other Details:
Languages:  eng; spa     Pagination:  304-9     Citation Subset:  IM    
Affiliation:
Neonatal Intensive Care Unit, Hospital de Pediatría SAMIC Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.
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