Document Detail


Risk of endophthalmitis after cataract surgery using different protocols for povidone- iodine preoperative disinfection.
MedLine Citation:
PMID:  16503776     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: The aim of this study was to assess the risk of postoperative endophthalmitis associated with different prophylactic protocols, using povidone-iodine disinfection of the skin and conjunctiva in patients undergoing cataract surgery over an 8-year period at Chang Gung Memorial Hospital (Kaohsiung, Taiwan). METHOD: This was a retrospective, comparative, case-controlled study. Data were collected on patients who received different prophylactic disinfection protocols prior to extracapsular cataract extraction with intraocular lens implantation between January 1992 and January 2000. Possible risk factors for the occurrence of postoperative endophthalmitis were analyzed. RESULTS: Medical charts for a total of 10,614 extracapsular cataract extraction surgeries performed during the 8-year period were reviewed, and 12 eyes that developed postoperative endophthalmitis were identified and analyzed. Another 120 eyes matched for age and gender of the patient were randomly selected as controls. Skin preparation with 5% povidone-iodine was associated with an increased risk of postoperative infection, compared to that of 10% povidoneiodine. On the conjunctiva, a lack of 5% povidone-iodine disinfection was associated with an increased risk of postoperative infection, compared to 5% povidone-iodine disinfection. CONCLUSIONS: Preoperative skin disinfection with 10% povidone-iodine and conjunctival disinfection with 5% povidone-iodine significantly reduced the relative risk of postoperative endophthalmitis.
Authors:
Pei-Chang Wu; Mien Li; Shun-Jen Chang; Mei-Ching Teng; Shew-Gin Yow; Shyi-Jang Shin; Hsi-Kung Kuo
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics     Volume:  22     ISSN:  1080-7683     ISO Abbreviation:  J Ocul Pharmacol Ther     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-28     Completed Date:  2006-05-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9511091     Medline TA:  J Ocul Pharmacol Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  54-61     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Infective Agents, Local / therapeutic use*
Case-Control Studies
Cataract Extraction*
Disinfection / methods*
Endophthalmitis / microbiology,  prevention & control*
Eye Infections / microbiology,  prevention & control*
Female
Humans
Male
Middle Aged
Postoperative Complications / microbiology,  prevention & control*
Povidone-Iodine / therapeutic use*
Preoperative Care
Retrospective Studies
Risk Factors
Skin / drug effects,  microbiology
Chemical
Reg. No./Substance:
0/Anti-Infective Agents, Local; 25655-41-8/Povidone-Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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