Document Detail

Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques.
MedLine Citation:
PMID:  11840241     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate risks of cranial ultrasound abnormalities among very-low-birth-weight (VLBW) infants conceived with fertility therapy (ovulation induction only or with assisted reproductive techniques [ART]) and of multiple gestation pregnancies. STUDY DESIGN: The incidences of cranial ultrasound abnormalities in 1473 VLBW infants conceived with and without fertility therapy and born of multiple versus singleton pregnancies were compared, using logistic regression models. RESULTS: Infants conceived with ART were less likely to have intraventricular hemorrhage (IVH). Twins and triplets had risks of cranial ultrasound abnormalities similar to those of singletons. Twins and triplets conceived with ART were at lower risk of IVH. CONCLUSION: VLBW infants conceived with ART do not appear to be at increased risk of cranial ultrasound abnormalities. Likewise, twins and triplets were not at increased risk of these abnormalities.
Jane E Stewart; Elizabeth N Allred; Margaret Collins; Jodi Abbott; Alan Leviton; Nigel Paneth; M Lynne Reuss; Mervyn Susser; Thomas Hegyi; Mark Hiatt; Ulana Sanocka; Farrokh Shahrivar; Linda J Van Marter; Petra Banogan; David Genest; Debra Heller; Susan Shen-Schwarz; Olaf Dammann; Karl C K Kuban; Marcello Pagano
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  22     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-02-12     Completed Date:  2002-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  37-45     Citation Subset:  IM    
Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
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MeSH Terms
Brain Damage, Chronic / ultrasonography
Cerebral Hemorrhage / epidemiology,  ultrasonography*
Confounding Factors (Epidemiology)
Infant, Newborn
Infant, Premature, Diseases / epidemiology,  ultrasonography*
Infant, Very Low Birth Weight*
Leukomalacia, Periventricular / epidemiology,  ultrasonography
Logistic Models
Placenta / pathology
Pregnancy Outcome
Reproductive Techniques, Assisted* / adverse effects
Risk Assessment

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