Document Detail

Risk of concurrent bacterial infection in preterm infants hospitalized due to respiratory syncytial virus infection.
MedLine Citation:
PMID:  17326757     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the risk of concurrent bacterial infection in preterm infants hospitalized due to respiratory syncytial virus (RSV) disease. PATIENTS AND METHODS: Retrospective cohort analysis of all infants hospitalized due to RSV infection between January 1, 2001 and July 31, 2005. Patients were identified by ICD-10 diagnosis of RSV infection including codes J21.0, J21.9, J12.1, J20.5 and B97.4. Medical charts were reviewed and RSV infection had to be confirmed by positive antigen detection test on nasopharyngeal aspirates. RESULTS: A total of 464 infants had been hospitalized due to RSV infection and 42 (9.1%) were born<37 weeks of gestational age. Concurrent bacterial infections were diagnosed by either positive blood or urine cultures, stool culture, tracheal aspirates or smears in 4 of 42 preterm (9.5%) compared to 13 of 422 term (3.1%) infants (p=0.017, RR 3.092, CI 95% 1.251-7.641). Excluding the infants admitted to the intensive care unit (ICU) the total rate of bacterial co-infection was 1.9%. Ten of 42 preterm (23.8%) compared to 25 of 422 term (5.2%) infants were referred to ICU (p<0.001, RR 3.349, CI 95% 1.882-5.959). All preterm infants had pneumonia, and isolates were Streptococcus pneumoniae, Chlamydia pneumoniae and Streptococcus pneumoniae with Haemophilus influenzae. Mean length of stay in preterm infants with bacterial co-infection was 22.3 days compared to 10.3 days without bacterial co-infection (p<0.006). CONCLUSION: The overall low risk of concurrent bacterial infection was significantly increased in preterm infants associated with prolonged hospitalization and ICU admission.
Bernhard Resch; Walter Gusenleitner; Wilhelm D Mueller
Related Documents :
20863437 - Congenital infections with trypanosoma cruzi or toxoplasma gondii are associated with d...
8933577 - Selective decontamination of the digestive tract: effect of cessation of routine applic...
18227767 - A five-year study in iran of ophthalmia neonatorum: prevalence and etiology.
18549387 - Increasing cause of cough among adults.
6331307 - Alternative medium for clostridium perfringens sporulation.
7170927 - Multiple gestations: management of pregnancy and delivery.
Publication Detail:
Type:  Journal Article     Date:  2007-02-26
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  96     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-29     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  495-8     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, Medical University Graz, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bacterial Infections / complications*
Cohort Studies
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases*
Respiratory Syncytial Virus Infections / complications*
Respiratory Syncytial Virus, Human*
Retrospective Studies
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Species-specific PCR detection of the fish pathogen, Vibrio anguillarum, using the amiB gene, which ...
Next Document:  The opinions of clinical staff regarding neonatal procedural pain in two Norwegian neonatal intensiv...