| Risk of complications after bariatric surgery among individuals with and without type 2 diabetes mellitus. | |
| | |
MedLine Citation:
|
PMID: 21880549 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Type 2 diabetes mellitus is highly prevalent in obese individuals. Bariatric surgery, promoted for reducing the medical problems of morbid obesity, has been increasingly recognized for its particular efficacy in treating diabetes. However, before bariatric surgery can be recommended for the treatment of diabetes, its safety in the diabetic population must be known. We assessed the odds of complications after bariatric surgery in patients with and without diabetes. METHODS: This was a retrospective cohort study. Using an administrative database from 7 Blue Cross/Blue Shield plans, we identified 22,288 subjects who had undergone bariatric surgery from 2002 to 2008. From this cohort, we selected 6754 pairs of surgical patients (1 with and 1 without diabetes) matched by age, gender, health plan, and year of surgery. With conditional logistic regression analysis, we determined the relative odds of postoperative complications for ≤12 months after surgery in the 2 groups. RESULTS: The mean age of the surgical patients was 46 years, and 79% were women. Postoperative complications were rare and comparable in those with and without diabetes. The most common complications were nausea, vomiting, and abdominal pain (8.8%), the need for a gastric revision procedure (5.0%), and upper endoscopy (2.3%). Select cardiac, infectious, and renal complications occurred more frequently in the diabetic group. The incidence of cardiac complications was greater in the 2-3-month and 4-6-month postoperative periods (odds ratio [OR] 1.7, P < .001), the incidence of infectious complications was greater in the 0-1-month (OR 1.3, P < .02) and 4-6-month (OR 1.8, P < .001) periods, and the incidence of renal complications was greater in the 2-3-month postoperative period (OR 4.6, P = .01). CONCLUSIONS: Our findings support the safety of bariatric surgery in obese individuals with diabetes, although management strategies to avert postoperative cardiac, infectious, and renal complications in this population might be warranted. |
| | |
Authors:
|
Kimberley E Steele; Gregory P Prokopowicz; Hsien-Yen Chang; Thomas Richards; Jeanne M Clark; Jonathan P Weiner; Sara N Bleich; Albert W Wu; Jodi B Segal |
Related Documents
:
|
12169659 - Ptp1b antisense oligonucleotide lowers ptp1b protein, normalizes blood glucose, and imp... 20825209 - Synthetic inositol phosphoglycans related to gpi lack insulin-mimetic activity. 10843189 - The gly-->arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucos... 17901049 - The direct involvement of sirt1 in insulin-induced insulin receptor substrate-2 tyrosin... 16248779 - Insulin resistance, obesity and the metabolic syndrome. is there a therapeutic role for... 2161429 - Hepatic protein phosphotyrosine phosphatase. dephosphorylation of insulin and epidermal... 6162929 - Autonomic disturbances in relation to sensorimotor peripheral neuropathy in diabetes me... 2928319 - Resistance to axonal degeneration after nerve compression in experimental diabetes. 18959599 - Rd lawrence lecture 2008: targeting glp-1 release as a potential strategy for the thera... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-15 |
Journal Detail:
|
Title: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Volume: - ISSN: 1878-7533 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-9-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101233161 Medline TA: Surg Obes Relat Dis Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ictal barking as a manifestation of temporal lobe epilepsy.
Next Document: The Value Prescription: Relative Value Theorem as a Call to Action.