| Risk of cancer among Hispanics with AIDS compared with the general population in Puerto Rico: 1987-2003. | |
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MedLine Citation:
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PMID: 20799513 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The risk of cancer among Hispanics with Acquired Immune Deficiency Syndrome (AIDS) in the United States and Puerto Rico (PR) has not been well described. The purpose of this study was to determine the risk of AIDS related and non-AIDS related cancers among Hispanics with AIDS in PR. METHODS: A probabilistic record linkage of the PR AIDS Surveillance Program and PR Central Cancer Registry databases was conducted. AIDS cases were grouped according to year of AIDS onset and antiretroviral therapy availability: 1987-1989 (limited availability), 1990-1995 (mono and dual therapy), and 1996-2003 (highly active antiretroviral therapy: HAART). Cancer risk was described using the standardized incidence ratios (SIR). RESULTS: A total of 612 cancers were identified after 3 months of AIDS diagnosis: 409 (66.7%) AIDS related and 203 (33.1%) non-AIDS related. Although a decreasing trend in the risk of AIDS and non-AIDS related cancers was observed, the risk for both remained higher in the AIDS group compared to the general population in PR. Non-AIDS related cancers with higher risk during the HAART availability were: oropharyngeal, anal, liver, larynx, eye and orbit, Hodgkin lymphoma, and vaginal. CONCLUSION: Hispanics with AIDS in PR consistently showed a greater risk of AIDS and non-AIDS related cancers compared to the general population in PR and that has not changed over time. |
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Authors:
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Farah A Ramírez-Marrero; Ellen Smit; Taína De La Torre-Feliciano; Javier Pérez-Irizarry; Sandra Miranda; Maritza Cruz; Nayda R Figueroa-Vallés; Carlos J Crespo; Cruz M Nazario |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Puerto Rico health sciences journal Volume: 29 ISSN: 0738-0658 ISO Abbreviation: P R Health Sci J Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303541 Medline TA: P R Health Sci J Country: Puerto Rico |
Other Details:
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Languages: eng Pagination: 256-64 Citation Subset: IM |
Affiliation:
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University of Puerto Rico School of Medicine, San Juan. farah.ramirez1@upr.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications* Adolescent Adult Female Hispanic Americans* Humans Male Middle Aged Neoplasms / epidemiology*, etiology* Puerto Rico / epidemiology Risk Factors Time Factors Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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CA096257/CA/NCI NIH HHS; P20 CA096256/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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