Document Detail

Risk of basal cell and squamous cell carcinoma in persons with prior cutaneous melanoma.
MedLine Citation:
PMID:  10848935     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Melanoma has been associated with an overall increase in actinic tumors, including actinic keratoses, as well as with noncutaneous malignancies. OBJECTIVE: Determine the risk of developing basal cell and squamous cell skin cancer in patients with prior cutaneous melanoma (actinic keratoses not encountered). METHODS: This retrospective study included 1396 white patients with prior cutaneous melanoma followed at the Roswell Park Cancer Institute in the period 1977-1978. The control group was the white population of the Detroit area in the same period (1977-1978). RESULTS: A total of 25 patients (18 males, 7 females) developed 35 basal cell and/or squamous cell carcinomas: 18 developed basal cell carcinomas, 2 squamous cell carcinomas, and 5 both. The calculated odds ratio was 3.49 (males 3.67, females 2.86, 95% confidence interval 1.52-8.00). No correlations were found with age, type, anatomic site, and length of follow-up of cutaneous melanoma. CONCLUSION: A history of cutaneous melanoma significantly increases the risk of basal cell and squamous cell skin cancer.
G Kroumpouzos; M M Konstadoulakis; H Cabral; C P Karakousis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  26     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-06-27     Completed Date:  2000-06-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  547-50     Citation Subset:  IM    
Department of Dermatology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
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MeSH Terms
Aged, 80 and over
Carcinoma, Basal Cell* / pathology
Carcinoma, Squamous Cell* / pathology
Confidence Intervals
Follow-Up Studies
Melanoma* / pathology
Middle Aged
Neoplasms, Second Primary*
Odds Ratio
Retrospective Studies
Risk Factors
Skin Neoplasms* / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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