Document Detail

Risk assessment of chlorpyrifos on rice and cabbage in China.
MedLine Citation:
PMID:  22210174     Owner:  NLM     Status:  Publisher    
Chlorpyrifos is a widely used organophosphorus insecticide in agricultural pest control. To understand the residue behavior of chlorpyrifos and to evaluate the dietary risk of chlorpyrifos residue in food in China, a number of residue studies were conducted on rice and cabbage. The supervised trials median residues (STMRs) for rice and cabbage were less than 0.010 and 0.227mgkg(-1), respectively. Only 7.4% and 13.3% of acceptable daily intake (ADI) (0-0.01mgkg(-1)bw) of chlorpyrifos is occupied by dietary daily intake to the Chinese adult and children, respectively, due to the consumption of rice and cabbage. These results on risk assessment were consistent with that of JMPR. Incorporation of market survey residue data gave a 5-fold reduction in the estimated exposures to chlorpyrifos. Concerning the acute exposure, the national estimated short-term intake (NESTI) represents 0.077% and 10.6% for rice and cabbage, respectively, of the acute reference dose (ARfD) (0-0.1mgkg(-1)bw). The application of chlorpyrifos at the recommended dose on rice and cabbage is unlikely to pose any public health issues if it is applied according to the good agriculture practices (GAPs) established by each country.
Chen Chen; Yongzhong Qian; Xianjin Liu; Chuanjiang Tao; Ying Liang; Yun Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-24
Journal Detail:
Title:  Regulatory toxicology and pharmacology : RTP     Volume:  -     ISSN:  1096-0295     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-1-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214983     Medline TA:  Regul Toxicol Pharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
Key Lab of Agro-product Quality and Safety, Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Republic of China.
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