| Risk of pregnancy-related hypertension within 5 years of exposure to drinking water contaminated with Escherichia coli O157:H7. | |
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MedLine Citation:
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PMID: 20695938 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors evaluated the risk for pregnancy-related hypertension among previously healthy women who conceived within 5 years of exposure to drinking water contaminated with Escherichia coli O157.H7 in Walkerton, Canada (2000). Chronic hypertension was defined as systolic/diastolic blood pressure >/=140/90 mm Hg before 20 weeks gestation; gestational hypertension was defined as new onset systolic/diastolic blood pressure >/=140/90 mm Hg >/=20 weeks gestation. The incidence of hypertension was compared between women who were asymptomatic during the outbreak to those who experienced acute gastroenteritis. Blood pressure data were available for 135 of 148 eligible pregnancies. The adjusted relative risks for chronic and gestational hypertension were 1.5 (95% confidence interval [CI]: 0.3-7.7) and 1.0 (95% CI: 0.4-2.5), respectively. Mean arterial pressure before 20 weeks gestation was 2.7 mm Hg higher in women who had acute gastroenteritis (95% CI: 0.05-5.4). A trend toward higher chronic hypertension and mean arterial pressure in early pregnancy was observed among women who experienced gastroenteritis after exposure to bacterially-contaminated drinking water. |
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Authors:
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Louise Moist; Jessica M Sontrop; Amit X Garg; William F Clark; Rita S Suri; Robert Gratton; Marina Salvadori; Immaculate Nevis; Jennifer J Macnab |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical hypertension (Greenwich, Conn.) Volume: 12 ISSN: 1751-7176 ISO Abbreviation: J Clin Hypertens (Greenwich) Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-10 Completed Date: 2010-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888554 Medline TA: J Clin Hypertens (Greenwich) Country: United States |
Other Details:
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Languages: eng Pagination: 613-20 Citation Subset: IM |
Copyright Information:
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(c) 2010 Wiley Periodicals, Inc. |
Affiliation:
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Division of Nephrology, Department of Medicine, Victoria Hospital-London Health Sciences Centre, 800 Commissioners Road East, London, Ontario, Canada. louise.moist@lhsc.on.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure / physiology Canada Cohort Studies Disease Outbreaks Escherichia coli Infections / complications, epidemiology, microbiology Escherichia coli O157* Female Gastroenteritis / complications*, microbiology* Humans Hypertension, Pregnancy-Induced / epidemiology*, etiology, physiopathology Incidence Pregnancy Pregnancy Complications, Cardiovascular / epidemiology*, etiology Prospective Studies Retrospective Studies Risk Factors Time Factors Water Microbiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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