Document Detail

Risk Prediction of Neonatal Therapeutic Intervention Scoring System in Vlbw and Elbw Preterms.
MedLine Citation:
PMID:  22320841     Owner:  NLM     Status:  Publisher    
Background:  NTISS is a therapy-based severity-of-illness index, This study was designed to evaluate whether a)NTISS with all parameters can predict the severity of illness with same accuracy both in VLBW and ELBW infants; b)the performance of NTISS can be increased by using only the significant variables. Methods:  All inborns of <1500g and <1500g outborns, transferred in the first 12 hours of postnatal life, were included. NTISS of 63 variables were performed to all, on the 24th hour. Predictive performance for the overall variables was assessed by AUC for Group-1(500-1499g), 2 (1000-1499 g) and 3 (500-999g). Variables with good prediction were detected for each group and a second AUC was assessed with only sensitive variables. ROC areas of all variables were compared with the ROC areas of sensitive variables. Results:  364 preterms were found eligible. The AUCs of Groups-1, 2 and 3 with all variables were 0.851; 0.834 and 0.749 respectively. Number of parameters with good prediction was 33 in Group-1; 30 in Group-2 and 18 in Group-3. The AUCs with only sensitive variables were 0.848 in Group-1; 0.821 in Group-2 and 0.823 in Group-3. When compared, increase in the description of outcome was significant only for Group-3 patients. (p:0.02). Conclusions:  NTISS with all parameters seems to be less predictive in ELBW infants. It is probably related with some interventions, done as a routine procedure in almost all ELBW preterms so, NTISS may be modified according to birth weight in order to obtain more sensitive prediction. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Nihal Oygur; Hakan Ongun; Osman Saka
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-9
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  -     ISSN:  1442-200X     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Akdeniz University Medical School, Department of Pediatrics, Division of Neonatology, Antalya-TURKEY Medical Park Hospital Department of Pediatrics, Antalya-TURKEY Akdeniz University Medical School, Department of Biostatistics, Antalya-TURKEY
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