Document Detail

Risk of Nocardial Infections With Anti-tumor Necrosis Factor Therapy.
MedLine Citation:
PMID:  23531994     Owner:  NLM     Status:  Publisher    
: Anti-tumor necrosis factor (anti-TNF) therapy is beneficial in the management of many chronic immune-mediated inflammatory diseases. However, its use is associated with increased risk of bacterial, fungal and viral infections. We present a case of cutaneous nocardiosis that occurred in a 61-year-old man, whose Crohn's disease was treated for nearly 1.5 years with infliximab. Prompt therapy with trimethoprim-sulfamethoxazole led to complete resolution. Only few cases of nocardiosis complicating anti-TNF therapy are reported in the literature. We present the case report and summary of the available literature with updates on the management and the treatment of the disease.
Tauseef Ali; Amarsha Chakraburtty; Sultan Mahmood; Michael Bronze
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-3-25
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  -     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-3-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
OU Physicians Center for Inflammatory Bowel Disease (TA), and Department of Internal Medicine (TA, AC, SM, MB), University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
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