Document Detail


Risk of Nocardial Infections With Anti-tumor Necrosis Factor Therapy.
MedLine Citation:
PMID:  23531994     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
: Anti-tumor necrosis factor (anti-TNF) therapy is beneficial in the management of many chronic immune-mediated inflammatory diseases. However, its use is associated with increased risk of bacterial, fungal and viral infections. We present a case of cutaneous nocardiosis that occurred in a 61-year-old man, whose Crohn's disease was treated for nearly 1.5 years with infliximab. Prompt therapy with trimethoprim-sulfamethoxazole led to complete resolution. Only few cases of nocardiosis complicating anti-TNF therapy are reported in the literature. We present the case report and summary of the available literature with updates on the management and the treatment of the disease.
Authors:
Tauseef Ali; Amarsha Chakraburtty; Sultan Mahmood; Michael Bronze
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-3-25
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  -     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-3-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
OU Physicians Center for Inflammatory Bowel Disease (TA), and Department of Internal Medicine (TA, AC, SM, MB), University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
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