| Risk factors for short- and long-term morbidity in children with esophageal atresia. | |
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MedLine Citation:
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PMID: 20123142 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To describe short- (first year of age) and long-term (after 1 year of age) outcome in patients with esophageal atresia and identify early predictive factors of morbidity in the first month of life. STUDY DESIGN: Charts of children with esophageal atresia born January 1990 to May 2005 were reviewed. A complicated evolution was defined as the occurrence of at least 1 complication: severe gastroesophageal reflux, esophageal stricture requiring dilatations, recurrent fistula needing surgery, need for gavage feeding for >or=3 months, severe tracheomalacia, chronic respiratory disease, and death. RESULTS: A total of 134 patients were included. Forty-nine percent of patients had a complicated evolution before 1 year of age, and 54% had a complicated evolution after 1 year. With bivariate analysis, predictive variables of a complicated evolution were demonstrated, including twin birth, preoperative tracheal intubation, birth weight <2500 g, long gap atresia, anastomotic leak, postoperative tracheal intubation >or=5 days, and inability to be fed orally by the end of the first month. After 1 year of age, the complicated evolution was only associated with long gap atresia and inability to be fed orally in the first month. A hospital stay >or=30 days was associated with a risk of a complicated evolution at 1 year and after 1 year of age (odds ratio, 9.3 [95% CI, 4.1-20.8] and 3.5 [95% CI, 1.6-7.6], respectively). CONCLUSION: Early factors are predictive of morbidity in children with esophageal atresia. |
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Authors:
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Julie Castilloux; Angela J Noble; Christophe Faure |
Publication Detail:
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Type: Journal Article Date: 2010-01-31 |
Journal Detail:
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Title: The Journal of pediatrics Volume: 156 ISSN: 1097-6833 ISO Abbreviation: J. Pediatr. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-13 Completed Date: 2010-05-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 755-60 Citation Subset: AIM; IM |
Affiliation:
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Division of Gastroenterology, Department of Pediatrics, H?pital Sainte-Justine, Universit? de Montr?al, Quebec, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Esophageal Atresia
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complications*,
surgery Esophageal Stenosis / etiology Female Gastroesophageal Reflux / etiology Humans Infant Length of Stay Male Photosensitivity Disorders Recurrence Respiratory Tract Diseases / etiology Risk Factors Tracheoesophageal Fistula / complications, surgery Tracheomalacia / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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