Document Detail


Risk Factors for Recurrent Urinary Tract Infection in Infants With Vesicoureteral Reflux During Prophylactic Treatment: Effect of Delayed Contrast Passage on Voiding Cystourethrogram.
MedLine Citation:
PMID:  21316084     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: To investigate the risk factors for recurrent urinary tract infection (UTI) in infants with vesicoureteral reflux (VUR) because little is known regarding the risk factors for breakthrough infection. METHODS: We compared children with infantile VUR with (20 boys, mean age 2.7 months) and without (20 boys and 4 girls, mean age 4.7 months) recurrent UTI. The factors compared included sex, timing of UTI episode, degree and bilaterality of the reflux, hydronephrosis, renal scar, associated congenital anomalies, voiding dysfunction, and delayed ureteral excretion of refluxed contrast on the voiding cystourethrogram. RESULTS: Univariate Cox survival-time regression analysis showed that a younger mean age at the first UTI, bilateral reflux, and grade 4-5 VUR and hydronephrosis on the initial ultrasound scan significantly increased the risk of recurrent UTI (P < .05 each). On multivariate analysis, high-grade (P = .009) and bilateral (P = .016) VUR were independently associated with an increased risk of recurrent UTI. Of the infants with and without recurrent UTI, 80% and 0%, respectively, presented with high-grade VUR, as shown by delayed contrast passage on the voiding cystourethrogram. A urodynamic study of 11 infants with recurrent UTI showed decreased bladder capacity in 2 infants and a larger residual volume in 1 infant. CONCLUSIONS: During the first year after birth, high-grade and bilateral VUR significantly increased the risk of recurrent UTI. Delayed contrast passage on the voiding cystourethrogram was significantly associated with an increased risk of recurrent UTI.
Authors:
Sungchan Park; Ji Yeon Han; Kun Suk Kim
Related Documents :
11429304 - Adolescent pregnancy, infant mortality, and source of payment for birth: alabama reside...
16223984 - Small-molecule inhibitor of vibrio cholerae virulence and intestinal colonization.
8525404 - Integration of control measures for malaria vectors in endemic areas of thailand.
21122164 - Genomic risk factors in sudden infant death syndrome.
11261914 - Patient-controlled spinal analgesia for labour and caesarean delivery.
8163764 - Respiratory syncytial virus triggered adult respiratory distress syndrome in infants: a...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-10
Journal Detail:
Title:  Urology     Volume:  -     ISSN:  1527-9995     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Urology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Republic of Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Tumor Size Is a Potential Predictor of Response to Tyrosine Kinase Inhibitors in Renal Cell Cancer.
Next Document:  Outcomes of Percutaneous Nephrolithotomy in Patients With Solitary Kidneys: a Single-center Experien...