Document Detail

Risk factors for recurrent small-for-gestational-age birth.
MedLine Citation:
PMID:  19670131     Owner:  NLM     Status:  MEDLINE    
The factors associated with recurrent small-for-gestational-age birth (R-SGA) have not been previously studied in a multiracial population. This is a retrospective cohort study of 5932 black and white women who had consecutive singleton first and second births in a Midwestern metropolis, from 1995 through 2004, to measure the risk and determine the factors associated with R-SGA. The rates for second-born small-for-gestational-age birth and R-SGA were 10.3% and 4.0%, respectively. Compared with mothers of firstborns who were appropriate for gestational age, mothers of firstborns who were small for gestation age had a higher risk of second-born small-for-gestational-age infants (relative risk [RR] = 3.93; 95% confidence interval [95% CI] = 3.36 to 4.59). Among those with firstborns who were small for gestational age, the odds ratio (OR) and 95% CI of R-SGA were higher for lean body mass index + poor gain (2.83; 1.20 to 6.69), blacks (1.58; 1.09 to 2.29), and smokers (1.61; 1.05 to 2.47). R-SGA occurs in 4% of second births and is responsible for 40% of second-born small-for-gestational-age infants. R-SGA is potentially preventable because of its association with potentially modifiable factors such as smoking and weight gain in pregnancy.
Felix A Okah; Jinwen Cai; Paul C Dew; Gerald L Hoff
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-05-20
Journal Detail:
Title:  American journal of perinatology     Volume:  27     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-24     Completed Date:  2010-03-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
Copyright Information:
Thieme Medical Publishers.
Department of Pediatrics, Children's Mercy Hospitals and Clinics/University of Missouri, Kansas City School of Medicine, Kansas City, Missouri 64108, USA.
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MeSH Terms
Body Mass Index
Cohort Studies
Gestational Age
Infant, Newborn
Infant, Small for Gestational Age*
Retrospective Studies
Risk Assessment
Risk Factors
Weight Gain

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