Document Detail

Risk Analysis of Unruptured Aneurysms Using Computational Fluid Dynamics Technology: Preliminary Results.
MedLine Citation:
PMID:  21903914     Owner:  NLM     Status:  Publisher    
BACKGROUND AND PURPOSE:The decision as to the treatment of incidental IAs is complex. There are no certain quantitative methods that can be used to evaluate the risk of rupture in IAs. In recent years, CFD technology has been recognized as a potential risk-analysis tool. The aim of this article was to propose a hemodynamic parameter, EL, to determine the effects of stable unruptured aneurysms and of those that ruptured during the subsequent observation period.MATERIALS AND METHODS:Four incidentally found ICA-PcomA aneurysms ruptured during the period of observation (ruptured-IAs). Another 26 unruptured aneurysms (stable-IAs) with similar location, size, and morphology were compared for the differences in hemodynamic factors, such as EL and WSS.RESULTS:The EL calculated at the ruptured-IAs was nearly 5 times higher on average than that at the stable-IAs (ruptured, 0.00374 ± 0.0011; stable, 0.000745 ± 0.0001 mW/mm(3), P < .001). However, there was no difference between the ruptured and stable groups according to the results of time-averaged WSS (P = .8) for ruptured- and stable-IAs. According to flow visualization, though the mean average inflow speed of ruptured-IAs was 2 times higher than that of the stable-IAs, the flow inside ruptured-IAs appeared to undergo longer resident tracks, with stronger impact on the aneurysm wall. On the contrary, the flow inside stable-IAs passed smoothly through the aneurysms.CONCLUSIONS:These preliminary results indicated that EL may be a useful parameter for the quantitative estimation of the risks of rupture for IAs.
Y Qian; H Takao; M Umezu; Y Murayama
Related Documents :
7788634 - A new use of the simpson percutaneous atherectomy catheter: resection of retained valve...
8606264 - Do excimer laser angioplasty and rotational atherectomy facilitate balloon angioplasty?...
8597614 - Occlusion of the superior mesenteric artery in a patient with polycythemia vera: resolu...
2095834 - Dissecting aneurysm of a coronary artery due to percutaneous transluminal balloon angio...
21292284 - Assessment and repair of aortic valve cusp prolapse: implications for valve-sparing pro...
8074134 - Case report: recurrent pneumothorax in a patient with rheumatoid arthritis.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-8
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  -     ISSN:  1936-959X     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
From The Jikei University School of Medicine, Tokyo, Japan; Waseda University, Tokyo, Japan; and Macquarie University, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Creation of Bifurcation-Type Elastase-Induced Aneurysms in Rabbits.
Next Document:  Interpretation Errors in CT Angiography of the Head and Neck and the Benefit of Double Reading.