Document Detail

Rings in the neonate.
MedLine Citation:
PMID:  21465878     Owner:  NLM     Status:  MEDLINE    
Neonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U RNP) as these are almost invariably present in NLE sera. The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.
C B Hackett; M A McAleer; B F O'Donnell
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Irish medical journal     Volume:  104     ISSN:  0332-3102     ISO Abbreviation:  Ir Med J     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-06     Completed Date:  2011-05-24     Revised Date:  2011-12-06    
Medline Journal Info:
Nlm Unique ID:  0430275     Medline TA:  Ir Med J     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  52-3     Citation Subset:  IM    
Department of Dermatology, The Children's University Hospital, Temple St, Dublin 1.
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MeSH Terms
Anti-Inflammatory Agents / administration & dosage
Hydrocortisone / administration & dosage
Lupus Erythematosus, Systemic* / congenital,  diagnosis,  therapy
Reg. No./Substance:
0/Anti-Inflammatory Agents; 50-23-7/Hydrocortisone

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